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Downregulation of miR-200b depressed the transcription factor endothelial transcription factor GATA binding protein 2 (GATA2) and vascular endothelial growth factor receptor 2 (VEGFR2) (Li et al., 2013), decreased collagen type ratio, dysregulated expression of skin neuropeptides (Nowak et al., 2021), lack of thrombin activated fibrinolytic inhibitor (Nass et al., 2010), decreased number of epidermal nerves ( Angiopoietin-like factor 4 (ANGPTL4) is a stromal cell protein that plays an important role in lipid and glucose metabolism and promotes keratinocyte migration, proliferation and angiogenesis

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Cytoarchitectonic criteria and histopathological validation were used to sample brain regions for snRNA-seq

Precipitation of protein from THP-1 cell conditioned media, followed by Western blotting analysis showed similar amounts of IL-1sRII in the supernatants of unstimulated and LPS-treated cells (Fig